Just completed a 2500 mile round trip. I found that the wind makes a lot more difference than anything. With a 20 MPH tailwind I regularly got 32 MPG (per the computer) for hundreds of miles. When the wind shifted to a crosswind in IL, the MPG went down to 29-30. Fighting a 25 mph headwind in OK and TX I got 28. My best MPG was in normal mode, but then again it was with a tailwind.
Get behind a truck on the freeway and watch the mile-o-meter go up 3-4 MPG.
Get behind a truck on the freeway and watch the mile-o-meter go up 3-4 MPG.