brfatal
Been here awhile...
If an engine is designed to primarily operate on premium fuel (91+ octane), then you will see a degradation in performance and economy. 87 and 89 octane fuels burn faster (and can cause pinging or knocking). The engine has knock sensors and can adjust the timing and injectors to compensate for the lower octane fuel. This in turn, causes lower HP output and a decrease in economy. On the other hand, a car designed to operate on 87 octane will not see ANY improvement or performance improvement by using 89 or 91 or 93 octane fuel.
Having said, that, there is NO advantage to fiddlefarting around with the 'stock' timing as the CPU does that anyways on the FLY as needed. This isn't your dad's muscle car.
The problem is that your knock sensors will only tell the ECU to pull timing AFTER it knocks. There are no such thing as predictive sensors. While all cars do knock, it's always considering a bad thing. Your ECU will pull timing when you're running lower octane and then slowly start to advance it. If you're still running lower octane it will detect knock again and retard the timing and advance, retard and advance in an endless cycle. In the long run I'd expect this affect the health of your engine, particularly your ringlands.